摘要帕唑帕尼 PazopanibPazopanib is an approved drug, is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineo...

摘要樂伐替尼 LenvatinibLenvatinib,also known as E7080,is a synthetic,orally available inhibitor of vascular endothelial growth factor receptor...

摘要卡博替尼 CabozantinibCabozantinib, also known as XL-184 or BMS-907351, is an orally bioavailable, small molecule receptor tyrosine kinase ...

摘要 Axitinib, also known as AG013736, is an orally bioavailable tyrosine kinase inhibitor.

摘要 KPT-330 SelinexorSelinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO1/CRM1 Inhibitor.

摘要格拉吉布 GlasdegibGlasdegib, also known as PF-04449913, is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling ...

摘要CAL-101 IdelalisibIdelalisib, also known as CAL-101, is a PI3K-delta inhibitor with potential immunomodulating and antineoplastic acti...

摘要IPI 145 DuvelisibAlso known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor o...

摘要 BAY 80-6946 CopanlisibCopanlisib also known as BAY 80-6946, is a potent phosphoinositide 3-kinase (PI3K) inhibitor.

摘要阿培利司 AlpelisibAlpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential...

摘要BMN 673 TalazoparibTalazoparib, also known as BMN-673 and MDV-3800,is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-...

摘要魯卡帕尼 RucaparibRucaparib is a tricyclic indole poly(ADP-Ribose) polymerase (PARP1) inhibitor with potential chemosensitizing, radiosens...

摘要尼拉帕尼 NiraparibNiraparib, also known as MK4827, is an orally active, potent and selective poly(ADP-Ribose) polymerase (PARP) inhibitor ...

摘要奧拉帕尼 OlaparibOlaparib, also known as AZD-2281 or KU-59436 , is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polym...

摘要拉羅替尼 LarotrectinibLarotrectinib, also known as ARRY-470 and LOXO-101, is an orally bioavailable, potent, ATP-competitive inhibitor of ...

摘要恩曲替尼 EntrectinibEntrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well ...

摘要 TemsirolimusTemsirolimus is an ester analog of rapamycin. Temsirolimus binds to and inhibits the mammalian target of rapamycin (mTOR),

摘要依維莫司 EverolimusEverolimus, also known as RAD001, is a derivative of the natural macrocyclic lactone sirolimus with immunosuppressant a...

摘要曲美替尼 TrametinibTrametinib, also known as GSK1120212, is a n orally bioavailable inhibitor of mitogen-activated protein kinase kinase (...

摘要考比替尼 CobimetinibCobimetinib, also known as GDC-0973 and XL-518, RG 7420, is an orally bioavailable small-molecule inhibitor of mitogen...

摘要 貝美替尼 BinimetinibBinimetinib, also known as MEK162 (ARRY-162), is an oral, highly selective MEK inhibitor.

摘要艾伏尼布 Ivosidenib Ivosidenib, also known as AG-120 and RG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1...

摘要伊那尼布 EnasidenibEnasidenib, also known as AG-221 and CC-90007, is a potent and selective IDH2 inhibitor with potential anticancer activ...

摘要瑞戈非尼 RegorafenibRegorafenib, also known as BAY 73-4506 ; is an orally bioavailable small molecule with potential antiangiogenic and an...

摘要魯索替尼 RuxolitinibAlso known as INC424 and INCB18424 or INCB018424, is an orally bioavailable Janus-associated kinase (JAK) inhibitor wi...

摘要厄達替尼 ErdafitinibErdafitinib, also known as JNJ-42756493, is a potent and selective orally bioavailable, pan fibroblast growth factor r...

摘要米哚妥林 MidostaurinMidostaurin, also known as PKC-412, PKC-412A and CGP 41251; is a synthetic indolocarbazole multikinase inhibitor with ...

摘要吉列替尼 GilteritinibGilteritinib, also known as ASP2215, is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity agains...

摘要 拉帕替尼 is a synthetic, orally-active quinazoline with potential antineoplastic activity.

摘要來那替尼 NeratinibNeratinib, also known as HKI-272 or PB272, is an orally available, irreversible inhibitor of the HER-2 receptor tyrosine...

摘要 奧瑞替尼 OsimertinibOsimertinib, also known as AZD-9291 and Mereletinib, is a third-generation EGFR inhibitor,

摘要達克替尼 DacomitinibDacomitinib, also known as PF-299 and PF-00299804 ; or PF299804, is an orally bioavailable, highly selective, second-g...

摘要吡昔替尼 PexidartinibPexidartinib, also know as PLX-3397, is a CSF1R inhibitor with IC50 of 20 nM in development by Plexxikon for the trea...

摘要瑞博西尼 RibociclibRibociclib Free Base, also known as LEE011, is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cy...

摘要帕布昔利布 PalbociclibPalbociclib, also known as PD-0332991, is an orally available cyclin-dependent kinase (CDK) inhibitor with potential ...

摘要玻瑪西尼 AbemaciclibAlso known as LY2835219, is orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1)...

摘要贊魯替尼 ZanubrutinibZanubrutinib, aslo known as BGB-3111, is a potent and highly selective small molecule BTK inhibitor for the potential...

摘要依魯替尼 IbrutinibIbrutinib, also known as PCI-32765, is a potent and orally active BTK inhibitor. Ibrutinib binds to and inhibits BTK act...

摘要阿卡替尼 AcalabrutinibAcalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton’s tyrosine kinase (BTK) with potent...

摘要康奈非尼 EncorafenibEncorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity...

摘要達帕菲尼 DabrafenibDabrafenib, also known as GSK2118436 , is an orally bioavailable inhibitor of B-raf (BRAF) protein with potential antin...

摘要維羅非尼 VemurafenibAlso known as PLX4032, RG7204 or RO5185426, is an orally bioavailable, ATP-competitive, small-molecule inhibitor of BR...

摘要普納替尼 PonatinibPonatinib is an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic...

摘要尼羅替尼 NilotinibNilotinib, also known as AMN107, is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-re...

摘要 DasatinibDasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family.